{"id":1318,"date":"2026-02-02T12:45:00","date_gmt":"2026-02-02T10:45:00","guid":{"rendered":"https:\/\/gynaikologos-komotini.gr\/proeklampsia\/"},"modified":"2026-10-07T10:59:10","modified_gmt":"2026-10-07T07:59:10","slug":"proeklampsia","status":"publish","type":"page","link":"https:\/\/gynaikologos-komotini.gr\/tr\/proeklampsia\/","title":{"rendered":"Preeklampsi"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1318\" class=\"elementor elementor-1318 elementor-446\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-54d9ce4c e-flex e-con-boxed e-con e-parent\" data-id=\"54d9ce4c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6586250c elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"6586250c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Preeklampsi<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-59137345 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"59137345\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Gebeli\u011fin bir komplikasyonu <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f45ef8e elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"f45ef8e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Preeklampsinin \u00d6nlenmesi ve Uzmanla\u015fm\u0131\u015f Maternal\u2013Fetal Y\u00f6netim\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-79b80d67 e-flex e-con-boxed e-con e-parent\" data-id=\"79b80d67\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-6d8a2e3a e-con-full e-flex e-con e-child\" data-id=\"6d8a2e3a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2f6b376c elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"2f6b376c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-35cf158d e-flex e-con-boxed e-con e-parent\" data-id=\"35cf158d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2e8bd75f e-con-full e-flex e-con e-child\" data-id=\"2e8bd75f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-398cea93 elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"398cea93\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6d3ec5e5 e-flex e-con-boxed e-con e-parent\" data-id=\"6d3ec5e5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4858ba44 e-con-full e-flex e-con e-child\" data-id=\"4858ba44\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2f0d24f elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"2f0d24f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><u>Preeklampsi nedir?<\/u><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d83b35 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"5d83b35\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi, <strong>gebeli\u011fin 20. haftas\u0131ndan sonra ortaya \u00e7\u0131kan multisistemik bir gebelik hastal\u0131\u011f\u0131d\u0131r<\/strong>. Yeni ba\u015flang\u0131\u00e7l\u0131 arteriyel hipertansiyon:<\/p><p><strong>Sistolik kan bas\u0131nc\u0131 \u2265140 mmHg ve\/veya diyastolik kan bas\u0131nc\u0131 \u226590 mmHg<\/strong> \u2014 iki \u00f6l\u00e7\u00fcm\u00fcn ortalamas\u0131 esas al\u0131narak \u2014<\/p><p>ile birlikte a\u015fa\u011f\u0131daki bulgulardan bir veya daha fazlas\u0131n\u0131n bulunmas\u0131yla karakterizedir:<\/p><ul><li><strong>Protein\u00fcri:<\/strong> PCR &gt;30 mg\/mmol, ACR &gt;8 mg\/mmol, rastgele idrar \u00f6rne\u011finde \u22652+ veya 24 saatlik idrarda &gt;0,3 g\/24 saat.<\/li><li>N\u00f6rolojik, hematolojik, renal, hepatik veya solunumsal bulgular\u0131 i\u00e7eren <strong>yeni geli\u015fen maternal organ disfonksiyonu<\/strong>.<\/li><li>Fetal b\u00fcy\u00fcme k\u0131s\u0131tl\u0131l\u0131\u011f\u0131 (FGR), anormal umbilikal arter Doppler bulgular\u0131, plasenta dekolman\u0131 veya anjiyojenik dengesizli\u011fi i\u00e7eren <strong>uteroplasental disfonksiyon<\/strong>.<img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-medium wp-image-2423\" src=\"https:\/\/gynaikologos-komotini.gr\/wp-content\/uploads\/2026\/10\/Preeklampsi_-Belirtiler-ve-Komplikasyonlar-500x333.png\" alt=\"\" width=\"500\" height=\"333\" \/><\/li><\/ul><p>Dolay\u0131s\u0131yla, yeni ba\u015flang\u0131\u00e7l\u0131 hipertansiyona maternal organ veya uteroplasental disfonksiyon e\u015flik ediyorsa <strong>preeklampsi tan\u0131s\u0131 i\u00e7in protein\u00fcri bulunmas\u0131 zorunlu de\u011fildir<\/strong>.<\/p><p>Preeklampsinin kesin nedeni tam olarak bilinmemektedir. \u00c7o\u011fu zaman herhangi bir belirti olmayabilir ve hastal\u0131k ilk kez rutin prenatal kontrolde kan bas\u0131nc\u0131n\u0131n \u00f6l\u00e7\u00fclmesi ve idrar incelemesi s\u0131ras\u0131nda saptanabilir. Bu nedenle gebelik boyunca d\u00fczenli kan bas\u0131nc\u0131 \u00f6l\u00e7\u00fcm\u00fc ve gerekti\u011finde uygun laboratuvar incelemeleri b\u00fcy\u00fck \u00f6nem ta\u015f\u0131r.<\/p><h4><strong>Gebelikte hipertansiyonun s\u0131n\u0131fland\u0131r\u0131lmas\u0131<\/strong><\/h4><h4><strong>Gebeli\u011fin 20. haftas\u0131ndan \u00f6nce<\/strong><\/h4><p><strong>Kronik hipertansiyon:<\/strong> gebelikten \u00f6nce mevcut olan veya gebeli\u011fin 20. haftas\u0131ndan \u00f6nce saptanan hipertansiyondur. Bilinen bir neden olmaks\u0131z\u0131n primer veya \u00f6rne\u011fin b\u00f6brek hastal\u0131\u011f\u0131na ba\u011fl\u0131 sekonder olabilir.<\/p><p><strong>Beyaz \u00f6nl\u00fck hipertansiyonu:<\/strong> muayenehanede kan bas\u0131nc\u0131n\u0131n \u2265140\/90 mmHg, evde ise &lt;135\/85 mmHg olmas\u0131d\u0131r.<\/p><p><strong>Maskeli hipertansiyon:<\/strong> muayenehanede kan bas\u0131nc\u0131n\u0131n &lt;140\/90 mmHg, evde ise \u2265135\/85 mmHg olmas\u0131d\u0131r.<\/p><h4>Gebeli\u011fin 20. haftas\u0131ndan sonra<\/h4><p><strong>Gestasyonel hipertansiyon:<\/strong> 20. haftadan sonra ilk kez ortaya \u00e7\u0131kan, protein\u00fcri veya preeklampsiye ait di\u011fer bulgular\u0131n e\u015flik etmedi\u011fi hipertansiyondur.<\/p><p><strong>Ge\u00e7ici gestasyonel hipertansiyon:<\/strong> ilk kez ortaya \u00e7\u0131kan ancak tekrarlanan \u00f6l\u00e7\u00fcmlerde normale d\u00f6nen hipertansiyondur.<\/p><p><strong>Preeklampsi:<\/strong> yeni ba\u015flang\u0131\u00e7l\u0131 hipertansiyona protein\u00fcri ve\/veya maternal organ disfonksiyonu ve\/veya uteroplasental disfonksiyonun e\u015flik etmesidir. N\u00f6rolojik bulgular, pulmoner \u00f6dem, hematolojik, renal veya hepatik bozukluklar, fetal b\u00fcy\u00fcme k\u0131s\u0131tl\u0131l\u0131\u011f\u0131, anormal Doppler bulgular\u0131 veya anjiyojenik dengesizlik g\u00f6r\u00fclebilir.<\/p><p><strong>Kronik hipertansiyon \u00fczerine geli\u015fen preeklampsi:<\/strong> kronik hipertansiyonu olan bir gebede preeklampsi ile uyumlu yeni maternal organ veya uteroplasental disfonksiyonun ortaya \u00e7\u0131kmas\u0131d\u0131r. Yeni geli\u015fen protein\u00fcri de g\u00f6r\u00fclebilir, ancak tek ba\u015f\u0131na tek tan\u0131 kriteri de\u011fildir.<\/p><p>Ge\u00e7ici gestasyonel hipertansiyonu olan kad\u0131nlar\u0131n yakla\u015f\u0131k <strong>%40&#8217;\u0131nda daha sonra gestasyonel hipertansiyon geli\u015febilir<\/strong>. Gebeli\u011fin erken d\u00f6nemlerinde gestasyonel hipertansiyon geli\u015fen kad\u0131nlarda ise preeklampsiye ilerleme riski daha y\u00fcksektir.<\/p><p>Bu nedenle gestasyonel hipertansiyonu olan gebeler, preeklampsi belirtileri, laboratuvar bozukluklar\u0131 ve fetal\/plasental disfonksiyon a\u00e7\u0131s\u0131ndan yak\u0131ndan izlenmelidir. \u0130zlem; klinik gereklili\u011fe g\u00f6re protein\u00fcri de\u011ferlendirmesini, seri fetal b\u00fcy\u00fcme ve amniyotik s\u0131v\u0131 \u00f6l\u00e7\u00fcmlerini, Doppler ultrasonografiyi ve se\u00e7ilmi\u015f olgularda <strong>PlGF ile sFlt-1\/PlGF oran\u0131<\/strong> gibi anjiyojenik belirte\u00e7leri i\u00e7erebilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4155ed0 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"4155ed0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><u>Preeklampsiye yakaland\u0131\u011f\u0131m\u0131 neden bilmem gerekir?<\/u><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d21a277 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d21a277\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi nispeten s\u0131k g\u00f6r\u00fclen bir gebelik komplikasyonudur ve d\u00fcnya genelinde yakla\u015f\u0131k <strong>her 100 gebeli\u011fin 2\u20138&#8217;ini<\/strong> etkiler.<\/p><p>Olgular\u0131n b\u00fcy\u00fck b\u00f6l\u00fcm\u00fc hafif seyretse de preeklampsi baz\u0131 kad\u0131nlarda h\u0131zla ilerleyerek hem anne hem de bebek a\u00e7\u0131s\u0131ndan ciddi ve ya\u015fam\u0131 tehdit edebilen bir tabloya d\u00f6n\u00fc\u015febilir.<\/p><p>Ciddi bulgular aras\u0131nda <strong>basit a\u011fr\u0131 kesicilerle ge\u00e7meyen \u015fiddetli ve s\u00fcrekli ba\u015f a\u011fr\u0131s\u0131, eklamptik n\u00f6betler, bilin\u00e7 de\u011fi\u015fiklikleri veya inme; bulan\u0131k g\u00f6rme veya skotom gibi g\u00f6rme bozukluklar\u0131; pulmoner \u00f6dem; trombositopeni, hemoliz veya yayg\u0131n damar i\u00e7i p\u0131ht\u0131la\u015fma; akut b\u00f6brek hasar\u0131; sa\u011f \u00fcst kar\u0131n veya epigastrik a\u011fr\u0131 ile birlikte ya da a\u011fr\u0131 olmaks\u0131z\u0131n karaci\u011fer enzimlerinde y\u00fckselme; plasenta dekolman\u0131, anormal anjiyojenik belirte\u00e7ler, fetal b\u00fcy\u00fcme k\u0131s\u0131tl\u0131l\u0131\u011f\u0131, anormal umbilikal arter Doppler bulgular\u0131 ve intrauterin fetal \u00f6l\u00fcm gibi uteroplasental bozukluklar<\/strong> yer al\u0131r.<\/p><p>Bu belirtiler ciddi kabul edilmelidir ve <strong>acil t\u0131bbi de\u011ferlendirme gerektirir<\/strong>. Herhangi bir \u015f\u00fcphe durumunda gebe kad\u0131n gecikmeden kad\u0131n do\u011fum uzman\u0131 veya do\u011fum \u00fcnitesi ile ileti\u015fime ge\u00e7melidir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d53ff4c elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d53ff4c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><u>Preeklampsi bebe\u011fimi nas\u0131l etkileyebilir?<\/u><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86e513d elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"86e513d\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi, plasentan\u0131n geli\u015fimi ve fonksiyonundaki bozukluklarla yak\u0131ndan ili\u015fkilidir.<\/p><p>Plasental disfonksiyon fet\u00fcse ula\u015fan oksijen ve besin miktar\u0131n\u0131 azaltabilir ve normal fetal b\u00fcy\u00fcmeyi etkileyerek <strong>fetal b\u00fcy\u00fcme k\u0131s\u0131tl\u0131l\u0131\u011f\u0131na (FGR)<\/strong> yol a\u00e7abilir.<\/p><p>Ayr\u0131ca bebe\u011fin \u00e7evresindeki amniyotik s\u0131v\u0131 miktar\u0131 azalabilir (<strong>oligohidramnios<\/strong>).<\/p><p>Plasenta fonksiyonlar\u0131n\u0131n ciddi \u015fekilde bozuldu\u011fu durumlarda fet\u00fcs\u00fcn iyilik hali \u00f6nemli \u00f6l\u00e7\u00fcde etkilenebilir ve en a\u011f\u0131r olgularda intrauterin fetal \u00f6l\u00fcm meydana gelebilir.<\/p><p>Anne ve fet\u00fcs\u00fcn yak\u0131n takibindeki temel ama\u00e7, y\u00fcksek risk alt\u0131ndaki fet\u00fcsleri zaman\u0131nda belirlemek ve gebeli\u011fi s\u00fcrd\u00fcrmenin riskleri ile premat\u00fcriteye ba\u011fl\u0131 riskleri dengeleyerek <strong>do\u011fum i\u00e7in en g\u00fcvenli zaman\u0131 belirlemektir<\/strong>.<\/p><h4>Anjiyojenik fakt\u00f6rler<\/h4><p>Anjiyojenik belirte\u00e7ler <strong>plasental disfonksiyon ve preeklampsi riski<\/strong> hakk\u0131nda \u00f6nemli bilgiler sa\u011flar.<\/p><p><strong>Plasental b\u00fcy\u00fcme fakt\u00f6r\u00fc (PlGF)<\/strong>, maternal \u00f6zellikler, kan bas\u0131nc\u0131 ve uterin arter Doppler de\u011ferlendirmesi ile birlikte birinci trimesterde uygulanan multiparametrik preeklampsi taramas\u0131n\u0131n bir par\u00e7as\u0131d\u0131r.<\/p><p>Bu yakla\u015f\u0131m, preterm preeklampsi geli\u015fme riski y\u00fcksek kad\u0131nlar\u0131n erken d\u00f6nemde belirlenmesine ve koruyucu aspirin tedavisinin ba\u015flanmas\u0131na olanak sa\u011flar.<\/p><p>Gebeli\u011fin daha ileri d\u00f6nemlerinde <strong>PlGF ve\/veya sFlt-1\/PlGF oran\u0131<\/strong>, preeklampsi \u015f\u00fcphesi bulunan, gestasyonel hipertansiyonu olan veya preeklampsiyi d\u00fc\u015f\u00fcnd\u00fcren belirtileri bulunan kad\u0131nlar\u0131n de\u011ferlendirilmesinde yararl\u0131 olabilir.<\/p><p>Bu biyobelirte\u00e7ler \u00f6zellikle <strong>\u00f6nceden mevcut protein\u00fcri, kronik hipertansiyon veya kronik b\u00f6brek hastal\u0131\u011f\u0131<\/strong> bulunan ve klasik tan\u0131 kriterlerinin yorumlanmas\u0131n\u0131n g\u00fc\u00e7 olabilece\u011fi gebelerde \u00f6nemlidir.<\/p><p>Anjiyojenik belirte\u00e7ler tek ba\u015f\u0131na bir tan\u0131 testi olarak de\u011fil; klinik bulgular, kan bas\u0131nc\u0131, laboratuvar incelemeleri ve fetal de\u011ferlendirme ile birlikte yorumlanmal\u0131d\u0131r.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-516697e4 e-flex e-con-boxed e-con e-parent\" data-id=\"516697e4\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ada7e0 elementor-widget elementor-widget-n-accordion\" data-id=\"9ada7e0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;expanded&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1620\" class=\"e-n-accordion-item\" open>\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"e-n-accordion-item-1620\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Kimler preeklampsi riski alt\u0131ndad\u0131r ve bu durum nas\u0131l \u00f6nlenebilir? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1620\" class=\"elementor-element elementor-element-55606d1 e-con-full e-flex e-con e-child\" data-id=\"55606d1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a91a05d elementor-widget elementor-widget-text-editor\" data-id=\"a91a05d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi her gebelikte ortaya \u00e7\u0131kabilir. Ancak <strong>kronik hipertansiyonu, daha \u00f6nce gestasyonel hipertansiyon veya preeklampsi \u00f6yk\u00fcs\u00fc, kronik b\u00f6brek hastal\u0131\u011f\u0131, diabetes mellitus, sistemik lupus eritematozus, antifosfolipid sendromu veya obezitesi<\/strong> bulunan kad\u0131nlarda risk daha y\u00fcksektir.<\/p><p>\u0130lk gebelik, anne ya\u015f\u0131n\u0131n \u226540 olmas\u0131, \u00f6nceki gebelikte plasenta dekolman\u0131, fetal b\u00fcy\u00fcme k\u0131s\u0131tl\u0131l\u0131\u011f\u0131 veya intrauterin fetal \u00f6l\u00fcm, y\u00fcksek maternal BMI, anne veya k\u0131z karde\u015fte preeklampsi \u00f6yk\u00fcs\u00fc ve \u00e7o\u011ful gebelik de riski art\u0131ran fakt\u00f6rler aras\u0131ndad\u0131r.<\/p><p>Bununla birlikte yaln\u0131zca klinik risk fakt\u00f6rleri, daha sonra preterm preeklampsi geli\u015ftirecek t\u00fcm kad\u0131nlar\u0131 belirleyemez.<\/p><p>Bu nedenle m\u00fcmk\u00fcn oldu\u011funda, klini\u011fimizde uyguland\u0131\u011f\u0131 gibi <strong>FMF algoritmas\u0131na dayal\u0131 birinci trimester multiparametrik tarama<\/strong>, daha ki\u015fiselle\u015ftirilmi\u015f bir risk de\u011ferlendirmesi sa\u011flar. Bu y\u00f6ntem maternal \u00f6zellikler ve t\u0131bbi \u00f6yk\u00fcy\u00fc biyofiziksel ve biyokimyasal belirte\u00e7lerle birle\u015ftirir.<\/p><p>Preterm preeklampsi a\u00e7\u0131s\u0131ndan y\u00fcksek riskli olarak de\u011ferlendirilen kad\u0131nlara klini\u011fimizde uygulanan koruyucu protokole g\u00f6re <strong>g\u00fcnde bir kez 160 mg aspirin<\/strong> \u00f6nerilir. Tedavinin tercihen birinci trimesterde ba\u015flanmas\u0131 ve <strong>gebeli\u011fin 36. haftas\u0131na kadar<\/strong> s\u00fcrd\u00fcr\u00fclmesi planlan\u0131r.<\/p><p>Preeklampsinin \u00f6nlenmesinde, herhangi bir kontrendikasyon bulunmad\u0131\u011f\u0131 s\u00fcrece, gebelik s\u0131ras\u0131nda <strong>d\u00fczenli fiziksel aktivite<\/strong> de \u00f6nemlidir.<\/p><p>Diyetle kalsiyum al\u0131m\u0131 yetersiz olan, \u00f6zellikle g\u00fcnl\u00fck kalsiyum al\u0131m\u0131 yakla\u015f\u0131k 900 mg&#8217;\u0131n alt\u0131nda bulunan kad\u0131nlarda, bireysel beslenme ve klinik ko\u015fullara g\u00f6re kalsiyum deste\u011fi de\u011ferlendirilmelidir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1621\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1621\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Preeklampsi nas\u0131l izlenir? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1621\" class=\"elementor-element elementor-element-54ad060 e-con-full e-flex e-con e-child\" data-id=\"54ad060\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-88b9b61 elementor-widget elementor-widget-text-editor\" data-id=\"88b9b61\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi tan\u0131s\u0131 konulduktan sonra <strong>anne ve fet\u00fcs\u00fcn daha yak\u0131n takibi<\/strong> gerekir.<\/p><p>Maternal takip; s\u0131k kan bas\u0131nc\u0131 \u00f6l\u00e7\u00fcmlerini ve hastal\u0131\u011f\u0131n ilerledi\u011fini d\u00fc\u015f\u00fcnd\u00fcren belirti ve bulgular\u0131n de\u011ferlendirilmesini i\u00e7erir. Laboratuvar incelemelerinde trombosit say\u0131s\u0131, b\u00f6brek fonksiyonlar\u0131 ve karaci\u011fer enzimleri de\u011ferlendirilir.<\/p><p>Preeklampsi tan\u0131s\u0131 kesinle\u015ftikten sonra protein\u00fcrinin tekrar tekrar miktar olarak \u00f6l\u00e7\u00fclmesi genellikle hastal\u0131\u011f\u0131n \u015fiddetini de\u011ferlendirmek a\u00e7\u0131s\u0131ndan yararl\u0131 de\u011fildir.<\/p><p>Hastal\u0131\u011f\u0131n \u015fiddetine g\u00f6re klinik ve laboratuvar de\u011ferlendirme yakla\u015f\u0131k <strong>haftada iki kez veya gerekti\u011finde daha s\u0131k<\/strong> yap\u0131labilir.<\/p><p>Fetal takip gerekti\u011finde fetal kalp h\u0131z\u0131n\u0131n de\u011ferlendirilmesini ve <strong>fetal b\u00fcy\u00fcme, amniyotik s\u0131v\u0131 miktar\u0131 ve Doppler velosimetrisini<\/strong> de\u011ferlendirmek amac\u0131yla seri ultrasonografileri i\u00e7erir.<\/p><p>Ultrasonografik takip s\u0131kl\u0131\u011f\u0131 gebelik haftas\u0131na, fetal b\u00fcy\u00fcmeye, Doppler bulgular\u0131na ve annenin klinik durumuna g\u00f6re ki\u015fiselle\u015ftirilir.<\/p><p>\u015eiddetli hipertansiyon, ilerleyici maternal organ disfonksiyonu, ciddi semptomlar veya fetal durumun bozuldu\u011funa ili\u015fkin bulgular varsa hastaneye yat\u0131\u015f gerekebilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1622\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1622\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Preeklampsi nas\u0131l tedavi edilir? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1622\" class=\"elementor-element elementor-element-0a382b2 e-con-full e-flex e-con e-child\" data-id=\"0a382b2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cda8c17 elementor-widget elementor-widget-text-editor\" data-id=\"cda8c17\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Preeklampsi ve \u015fiddetli gestasyonel hipertansiyon h\u0131zl\u0131 bir \u015fekilde k\u00f6t\u00fcle\u015febilir. Bu nedenle hastane de\u011ferlendirmesi ve bir\u00e7ok olguda hastaneye yat\u0131\u015f gerekir.<\/p><p>Hastal\u0131\u011f\u0131 stabil olan, kan bas\u0131nc\u0131 \u015fiddetli hipertansiyon d\u00fczeyinde bulunmayan ve maternal veya fetal komplikasyonu olmayan se\u00e7ilmi\u015f kad\u0131nlar, <strong>yak\u0131n ve g\u00fcvenilir anne-fet\u00fcs takibi sa\u011flanabildi\u011fi takdirde<\/strong> ayaktan izlenebilir.<\/p><h4>Antihipertansif tedavi<\/h4><p>Antihipertansif tedavinin amac\u0131, uteroplasental perf\u00fczyonu korurken \u015fiddetli hipertansiyona ba\u011fl\u0131 maternal komplikasyon riskini azaltmakt\u0131r.<\/p><p>Pratik tedavi hedefi <strong>sistolik kan bas\u0131nc\u0131n\u0131 yakla\u015f\u0131k 110\u2013140 mmHg aral\u0131\u011f\u0131nda ve diyastolik kan bas\u0131nc\u0131n\u0131 yakla\u015f\u0131k 85 mmHg d\u00fczeyinde tutmakt\u0131r<\/strong>.<\/p><p>Kan bas\u0131nc\u0131 a\u015f\u0131r\u0131 d\u00fc\u015ferse, \u00f6zellikle diyastolik bas\u0131n\u00e7 yakla\u015f\u0131k 80 mmHg&#8217;n\u0131n alt\u0131na iner veya hipotansiyon belirtileri ortaya \u00e7\u0131karsa tedavi yeniden de\u011ferlendirilmeli ve gerekirse doz azalt\u0131lmal\u0131d\u0131r.<\/p><p>Orta dereceli hipertansiyon genellikle oral ila\u00e7larla tedavi edilebilir. Hastan\u0131n \u00f6zelliklerine ve klinik duruma g\u00f6re s\u0131k kullan\u0131lan ila\u00e7lar aras\u0131nda <strong>labetalol, nifedipin ve metildopa<\/strong> bulunur.<\/p><p><strong>\u015eiddetli hipertansiyon (\u2265160\/110 mmHg)<\/strong> acil tedavi gerektirir. Klinik duruma ve uygulanan protokole g\u00f6re oral h\u0131zl\u0131 etkili nifedipin veya intraven\u00f6z labetalol ya da hidralazin kullan\u0131labilir.<\/p><p>Gerekti\u011finde antihipertansif tedavi do\u011fum s\u0131ras\u0131nda da s\u00fcrd\u00fcr\u00fcl\u00fcr ve kan bas\u0131nc\u0131 yak\u0131ndan takip edilir.<\/p><h4>Magnezyum s\u00fclfat<\/h4><p><strong>Eklampsi<\/strong> geli\u015fen gebelere tekrarlayan n\u00f6betleri \u00f6nlemek amac\u0131yla intraven\u00f6z magnezyum s\u00fclfat verilmelidir.<\/p><p>Magnezyum s\u00fclfat ayr\u0131ca ciddi \u00f6zellikler g\u00f6steren preeklampside, \u00f6zellikle \u015fiddetli hipertansiyona n\u00f6rolojik belirtilerin e\u015flik etti\u011fi veya eklampsi riskinin y\u00fcksek oldu\u011fu kad\u0131nlarda n\u00f6bet profilaksisi amac\u0131yla kullan\u0131l\u0131r.<\/p><p>Magnezyum s\u00fclfat eklamptik n\u00f6betlerin ortaya \u00e7\u0131kma ve tekrarlama riskini belirgin \u015fekilde azalt\u0131r.<\/p><h4>Do\u011fum<\/h4><p><strong>Preeklampsinin tek kesin tedavisi do\u011fumdur.<\/strong> Bununla birlikte do\u011fumun en uygun zaman\u0131 gebelik haftas\u0131na ve hem annenin hem de fet\u00fcs\u00fcn durumuna ba\u011fl\u0131d\u0131r.<\/p><p>Gebelik haftas\u0131ndan ba\u011f\u0131ms\u0131z olarak anne veya fet\u00fcs\u00fcn durumunda k\u00f6t\u00fcle\u015fme gebeli\u011fin devam\u0131n\u0131 g\u00fcvensiz hale getiriyorsa erken do\u011fum gerekebilir.<\/p><p>\u00d6nemli endikasyonlar aras\u0131nda <strong>eklampsi veya ilerleyici n\u00f6rolojik belirtiler; ge\u00e7meyen \u015fiddetli ba\u015f a\u011fr\u0131s\u0131 veya tekrarlayan g\u00f6rsel skotomlar; uygun antihipertansif tedaviye ra\u011fmen kontrol alt\u0131na al\u0131namayan \u015fiddetli hipertansiyon; pulmoner \u00f6dem; ciddi veya ilerleyici trombositopeni; hemoliz veya klinik olarak \u00f6nemli koag\u00fclopati; ilerleyici renal veya hepatik disfonksiyon; ciddi hepatik komplikasyonlar; plasenta dekolman\u0131 ve belirgin fetal bozulma bulgular\u0131<\/strong> bulunur.<\/p><h5>Fetal viabilite s\u0131n\u0131r\u0131ndan \u00f6nce<\/h5><p>Neonatal viabilite s\u0131n\u0131r\u0131ndan \u00f6nce ortaya \u00e7\u0131kan \u00e7ok erken ve \u015fiddetli preeklampside, maternal riskler ve fet\u00fcs a\u00e7\u0131s\u0131ndan son derece k\u00f6t\u00fc prognoz ayr\u0131nt\u0131l\u0131 olarak de\u011ferlendirilmelidir.<\/p><p>Tedavi maternal\u2013fetal t\u0131p konusunda uzmanla\u015fm\u0131\u015f \u00fc\u00e7\u00fcnc\u00fc basamak bir merkezde ki\u015fiselle\u015ftirilmelidir. Gebeli\u011fin devam\u0131n\u0131n anne a\u00e7\u0131s\u0131ndan kabul edilemez bir risk olu\u015fturdu\u011fu durumlarda gebeli\u011fin sonland\u0131r\u0131lmas\u0131 g\u00fcndeme gelebilir.<\/p><h5>34. haftadan \u00f6nce<\/h5><p>Anne ve fet\u00fcs\u00fcn durumu stabil oldu\u011fu ve acil do\u011fum endikasyonu bulunmad\u0131\u011f\u0131 s\u00fcrece uygun bir \u00fc\u00e7\u00fcnc\u00fc basamak merkezde <strong>bekleyici yakla\u015f\u0131m<\/strong> uygulanabilir.<\/p><p>Ama\u00e7, a\u015f\u0131r\u0131 premat\u00fcriteye ba\u011fl\u0131 komplikasyonlar\u0131 azaltmak i\u00e7in gebeli\u011fi g\u00fcvenli bi\u00e7imde uzatmak, ancak anne veya fet\u00fcs\u00fcn durumunda bozulma meydana gelirse do\u011fumu geciktirmemektir.<\/p><h5>34+0\u201336+6 hafta<\/h5><p>Do\u011fum karar\u0131 annenin ve fet\u00fcs\u00fcn durumuna, hastal\u0131\u011f\u0131n \u015fiddetine ve neonatal fakt\u00f6rlere g\u00f6re ki\u015fiselle\u015ftirilmelidir.<\/p><p>Do\u011fum maternal komplikasyonlar\u0131 azaltabilir; gebeli\u011fin g\u00fcvenli bi\u00e7imde devam ettirilmesi ise ge\u00e7 premat\u00fcriteye ba\u011fl\u0131 neonatal komplikasyonlar\u0131 azaltabilir.<\/p><h5>37. haftadan itibaren<\/h5><p>Preeklampsisi olan kad\u0131nlarda genel olarak <strong>37. gebelik haftas\u0131ndan itibaren do\u011fum planlanmal\u0131d\u0131r<\/strong>.<\/p><p>Preeklampsi bulunmayan gestasyonel veya kronik hipertansiyonda do\u011fum zaman\u0131; kan bas\u0131nc\u0131 kontrol\u00fc, anne ve fet\u00fcs\u00fcn durumu ve obstetrik fakt\u00f6rlere g\u00f6re belirlenir.<\/p><h4>Antenatal kortikosteroidler<\/h4><p>\u00d6zellikle 34. gebelik haftas\u0131ndan \u00f6nce, <strong>\u00f6n\u00fcm\u00fczdeki 7 g\u00fcn i\u00e7inde erken do\u011fum olas\u0131l\u0131\u011f\u0131 y\u00fcksek olan kad\u0131nlara antenatal kortikosteroid uygulanmas\u0131<\/strong> \u00f6nerilir.<\/p><p>Bu tedavi neonatal solunum morbiditesini ve premat\u00fcriteye ba\u011fl\u0131 di\u011fer komplikasyonlar\u0131, \u00f6zellikle respiratuvar distres sendromu ve intraventrik\u00fcler kanama riskini azaltarak neonatal sonu\u00e7lar\u0131 iyile\u015ftirir.<\/p><p>Genellikle <strong>tek bir antenatal kortikosteroid k\u00fcr\u00fc<\/strong> uygulan\u0131r.<\/p><p>Erken do\u011fum riski devam eden se\u00e7ilmi\u015f kad\u0131nlarda gebelik haftas\u0131, ilk k\u00fcrden sonra ge\u00e7en s\u00fcre ve uygulanmakta olan klinik k\u0131lavuza g\u00f6re tekrar k\u00fcr\u00fc de\u011ferlendirilebilir.<\/p><p><strong>34+0\u201336+6 haftalar aras\u0131nda<\/strong>, daha \u00f6nce antenatal kortikosteroid almam\u0131\u015f ve \u00f6n\u00fcm\u00fczdeki 7 g\u00fcn i\u00e7inde do\u011fum yapma riski y\u00fcksek olan se\u00e7ilmi\u015f kad\u0131nlarda bireysel de\u011ferlendirme sonras\u0131nda kortikosteroid uygulanmas\u0131 d\u00fc\u015f\u00fcn\u00fclebilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1623\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1623\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Yeni tedavi se\u00e7enekleri <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1623\" class=\"elementor-element elementor-element-d1e2e41 e-con-full e-flex e-con e-child\" data-id=\"d1e2e41\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2565b86 elementor-widget elementor-widget-text-editor\" data-id=\"2565b86\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>G\u00fcn\u00fcm\u00fczde <strong>preeklampsinin tek kesin tedavisi do\u011fumdur<\/strong>.<\/p><p>Hastal\u0131\u011f\u0131n temel patofizyolojisini, \u00f6zellikle preeklampsiyle ili\u015fkili <strong>anjiyojenik dengesizlik, endotelyal disfonksiyon ve inflamatuvar yan\u0131t\u0131<\/strong> de\u011fi\u015ftirmeyi ama\u00e7layan bir\u00e7ok tedavi ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r.<\/p><p>Statinler, metformin ve \u00e7e\u015fitli hedefe y\u00f6nelik biyolojik veya antikor temelli tedaviler ara\u015ft\u0131r\u0131lm\u0131\u015f veya halen ara\u015ft\u0131r\u0131lmaktad\u0131r.<\/p><p>Bu yakla\u015f\u0131mlar\u0131n temel amac\u0131 hastal\u0131\u011f\u0131n ilerlemesini geciktirmek ve gebeli\u011fi anne ve fet\u00fcs a\u00e7\u0131s\u0131ndan g\u00fcvenli bi\u00e7imde uzatabilmektir.<\/p><p>Ancak g\u00fcn\u00fcm\u00fczde bu tedaviler halen ara\u015ft\u0131rma a\u015famas\u0131ndad\u0131r ve yerle\u015fik korunma, takip ve do\u011fum stratejilerinin yerini almamaktad\u0131r.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1624\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1624\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Do\u011fumdan sonra ne olur? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1624\" class=\"elementor-element elementor-element-82c9465 e-con-full e-flex e-con e-child\" data-id=\"82c9465\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cbe88ff elementor-widget elementor-widget-text-editor\" data-id=\"cbe88ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li>Preeklampsi do\u011fumdan hemen sonra tamamen ortadan kalkmayabilir. Ayr\u0131ca <strong>do\u011fum sonras\u0131 d\u00f6nemde ilk kez hipertansiyon veya preeklampsi geli\u015febilir ya da mevcut hipertansiyon k\u00f6t\u00fcle\u015febilir<\/strong>.<\/li><li>Bu nedenle \u00f6zellikle do\u011fumdan sonraki ilk hafta boyunca kan bas\u0131nc\u0131 takibine devam edilmelidir.<\/li><li>Antihipertansif tedavi gerekti\u011finde do\u011fumdan sonra da s\u00fcrd\u00fcr\u00fcl\u00fcr ve postpartum kan bas\u0131nc\u0131na g\u00f6re ayarlan\u0131r. Ama\u00e7 hem \u015fiddetli hipertansiyondan hem de kan bas\u0131nc\u0131n\u0131n a\u015f\u0131r\u0131 d\u00fc\u015f\u00fcr\u00fclmesinden ka\u00e7\u0131nmakt\u0131r.<\/li><li><strong>Emzirme \u00f6nerilir<\/strong> ve antihipertansif tedavi genellikle emzirme ile uyumlu ila\u00e7lar aras\u0131ndan se\u00e7ilebilir.<\/li><li>Hipertansiyonun ve renal, hepatik veya hematolojik bozukluklar\u0131n d\u00fczelip d\u00fczelmedi\u011fini do\u011frulamak amac\u0131yla postpartum klinik ve laboratuvar kontrol\u00fc gerekir. Devam eden anormallikler daha ileri ara\u015ft\u0131rma gerektirir.<\/li><li>Gestasyonel hipertansiyon veya preeklampsi ge\u00e7iren kad\u0131nlarda ilerleyen ya\u015famda <strong>kronik hipertansiyon ve kardiyovask\u00fcler hastal\u0131k riski artm\u0131\u015ft\u0131r<\/strong>. Bu nedenle uzun d\u00f6nem kardiyovask\u00fcler risk de\u011ferlendirmesi, sa\u011fl\u0131kl\u0131 ya\u015fam tarz\u0131 konusunda dan\u0131\u015fmanl\u0131k ve d\u00fczenli takip \u00f6nerilir.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1625\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"6\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1625\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Gelecekteki bir hamilelikte preeklampsi ya\u015far m\u0131y\u0131m? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1625\" class=\"elementor-element elementor-element-ae409ce e-con-full e-flex e-con e-child\" data-id=\"ae409ce\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2c6030b elementor-widget elementor-widget-text-editor\" data-id=\"2c6030b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Daha \u00f6nce preeklampsi ge\u00e7irilmi\u015f olmas\u0131 sonraki gebelikte hastal\u0131\u011f\u0131n tekrarlama riskini art\u0131r\u0131r. Ancak riskin b\u00fcy\u00fckl\u00fc\u011f\u00fc, \u00f6nceki preeklampsinin <strong>hangi gebelik haftas\u0131nda ortaya \u00e7\u0131kt\u0131\u011f\u0131na, hastal\u0131\u011f\u0131n \u015fiddetine ve e\u015flik eden maternal veya fetal komplikasyonlara<\/strong> \u00f6nemli \u00f6l\u00e7\u00fcde ba\u011fl\u0131d\u0131r.<\/p><p>Genel olarak daha \u00f6nce preeklampsi ge\u00e7irmi\u015f kad\u0131nlar\u0131n yakla\u015f\u0131k <strong>alt\u0131da birinde<\/strong> sonraki gebelikte yeniden preeklampsi geli\u015febilir.<\/p><p>\u00c7ok erken ba\u015flang\u0131\u00e7l\u0131 veya \u015fiddetli preeklampsi ge\u00e7iren kad\u0131nlarda tekrarlama riski belirgin olarak daha y\u00fcksektir. \u00d6nceki gebelikte a\u011f\u0131r preeklampsi nedeniyle \u00e7ok erken do\u011fum yapmak zorunda kalan kad\u0131nlar \u00f6zellikle y\u00fcksek riskli bir gruptur.<\/p><p>Daha \u00f6nce gestasyonel hipertansiyon ge\u00e7iren kad\u0131nlarda da sonraki gebelikte hem gestasyonel hipertansiyon hem de preeklampsi geli\u015fme riski artm\u0131\u015ft\u0131r.<\/p><p>Ayr\u0131ca gebeli\u011fin hipertansif hastal\u0131klar\u0131n\u0131 ge\u00e7irmi\u015f kad\u0131nlar\u0131n, sonraki gebelikte kan bas\u0131n\u00e7lar\u0131 normal olsa bile <strong>gebelik haftas\u0131na g\u00f6re k\u00fc\u00e7\u00fck (SGA) bir fet\u00fcs<\/strong> ta\u015f\u0131ma riskleri artm\u0131\u015ft\u0131r.<\/p><p>Ek risk fakt\u00f6rlerinin bulunmas\u0131, \u00f6nceki preeklampsinin \u00e7ok erken ortaya \u00e7\u0131km\u0131\u015f olmas\u0131, hastal\u0131\u011f\u0131n tekrarlamas\u0131 veya \u00f6nceki maternal\/fetal komplikasyonlar, baz\u0131 y\u00fcksek riskli gruplarda tekrarlama olas\u0131l\u0131\u011f\u0131n\u0131 <strong>%50&#8217;ye kadar<\/strong> y\u00fckseltebilir.<\/p><p>Bu nedenle bu kad\u0131nlarda sonraki gebeliklerden \u00f6nce <strong>prekonsepsiyonel dan\u0131\u015fmanl\u0131k<\/strong>, gebeli\u011fin erken d\u00f6neminden itibaren yak\u0131n takip ve <strong>birinci trimester preeklampsi taramas\u0131<\/strong> \u00f6zellikle \u00f6nemlidir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-133a7421 e-con-full e-flex elementor-invisible e-con e-parent\" data-id=\"133a7421\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_video_link&quot;:&quot;https:\\\/\\\/youtu.be\\\/TMZtZtylxI4&quot;,&quot;background_play_on_mobile&quot;:&quot;yes&quot;,&quot;background_privacy_mode&quot;:&quot;yes&quot;,&quot;animation&quot;:&quot;fadeIn&quot;}\">\n\t\t<div class=\"elementor-background-video-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-video-embed\" role=\"presentation\"><\/div>\n\t\t\t\t\t\t<\/div><div class=\"elementor-element elementor-element-1c4d33df e-con-full e-flex e-con e-child\" data-id=\"1c4d33df\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7dbcf5c1 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"7dbcf5c1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Y\u00fcksek standartlarda t\u0131bbi hizmetler Komotini&#8217;deki Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum Uzman\u0131 Alexandros Maina taraf\u0131ndan.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-37b9323e elementor-widget elementor-widget-button\" data-id=\"37b9323e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"\/tr\/epikoinonia\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-right\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M190.5 66.9l22.2-22.2c9.4-9.4 24.6-9.4 33.9 0L441 239c9.4 9.4 9.4 24.6 0 33.9L246.6 467.3c-9.4 9.4-24.6 9.4-33.9 0l-22.2-22.2c-9.5-9.5-9.3-25 .4-34.3L311.4 296H24c-13.3 0-24-10.7-24-24v-32c0-13.3 10.7-24 24-24h287.4L190.9 101.2c-9.8-9.3-10-24.8-.4-34.3z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Doktorla randevu al\u0131n <\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Preeklampsi Gebeli\u011fin bir komplikasyonu Preeklampsinin \u00d6nlenmesi ve Uzmanla\u015fm\u0131\u015f Maternal\u2013Fetal Y\u00f6netim Preeklampsi nedir? Preeklampsi, gebeli\u011fin 20. haftas\u0131ndan sonra ortaya \u00e7\u0131kan multisistemik bir gebelik hastal\u0131\u011f\u0131d\u0131r. Yeni ba\u015flang\u0131\u00e7l\u0131 arteriyel<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":-1,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-1318","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Preeklampsi<\/title>\n<meta name=\"description\" content=\"Preeklampsi, gebeli\u011fin 20. haftas\u0131ndan sonra ortaya \u00e7\u0131kan multisistemik bir gebelik hastal\u0131\u011f\u0131d\u0131r. Yeni ba\u015flang\u0131\u00e7l\u0131 arteriyel hipertansiyon:Sistolik kan bas\u0131nc\u0131 \u2265140 mmHg ve\/veya diyastolik kan bas\u0131nc\u0131 \u226590 mmHg \u2014 iki \u00f6l\u00e7\u00fcm\u00fcn ortalamas\u0131 esas al\u0131narak \u2014ile birlikte a\u015fa\u011f\u0131daki bulgulardan bir veya daha fazlas\u0131n\u0131n bulunmas\u0131yla karakterizedir:Protein\u00fcri\/N\u00f6rolojik, hematolojik, renal, hepatik veya solunumsal bulgular\u0131 i\u00e7eren yeni geli\u015fen maternal organ disfonksiyonu.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gynaikologos-komotini.gr\/tr\/proeklampsia\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preeklampsi\" \/>\n<meta property=\"og:description\" content=\"Preeklampsi, gebeli\u011fin 20. haftas\u0131ndan sonra ortaya \u00e7\u0131kan multisistemik bir gebelik hastal\u0131\u011f\u0131d\u0131r. Yeni ba\u015flang\u0131\u00e7l\u0131 arteriyel hipertansiyon:Sistolik kan bas\u0131nc\u0131 \u2265140 mmHg ve\/veya diyastolik kan bas\u0131nc\u0131 \u226590 mmHg \u2014 iki \u00f6l\u00e7\u00fcm\u00fcn ortalamas\u0131 esas al\u0131narak \u2014ile birlikte a\u015fa\u011f\u0131daki bulgulardan bir veya daha fazlas\u0131n\u0131n bulunmas\u0131yla karakterizedir:Protein\u00fcri\/N\u00f6rolojik, hematolojik, renal, hepatik veya solunumsal bulgular\u0131 i\u00e7eren yeni geli\u015fen maternal organ disfonksiyonu.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/gynaikologos-komotini.gr\/tr\/proeklampsia\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0391\u03bb\u03ad\u03be\u03b1\u03bd\u03b4\u03c1\u03bf\u03c2 \u039c\u03ac\u03b9\u03bd\u03b1\u03c2 MD, PhD\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-07T07:59:10+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data1\" content=\"18 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/tr\\\/proeklampsia\\\/\",\"url\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/tr\\\/proeklampsia\\\/\",\"name\":\"Preeklampsi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/tr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/tr\\\/proeklampsia\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/tr\\\/proeklampsia\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/gynaikologos-komotini.gr\\\/wp-content\\\/uploads\\\/2026\\\/10\\\/Preeklampsi_-Belirtiler-ve-Komplikasyonlar-500x333.png\",\"datePublished\":\"2026-02-02T10:45:00+00:00\",\"dateModified\":\"2026-10-07T07:59:10+00:00\",\"description\":\"Preeklampsi, gebeli\u011fin 20. haftas\u0131ndan sonra ortaya \u00e7\u0131kan multisistemik bir gebelik hastal\u0131\u011f\u0131d\u0131r. 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